ME 6xx

Tissue Engineering

3 credit hours
Fall semester

instructor(s)
	Biomedical Engineering Faculty

prerequisites
	Graduate standing

description
This course presents a comprehensive background to the discipline of tissue
 engineering including the biomaterials used for tissue engineering,
  mechanical, electrical, and chemical stressors which can effect tissue
 remodeling, and the clinical application of tissue engineering.

text
	To be decided.

outline
	Topic	Number of Lectures
Definition and Scope of Tissue Engineering	1	
Introduction to Developmental Biology	2
Cell, Tissue, and Organ Differentiation	3
Hypertrophy vs. Hyperplasia	1
Effect of Electrical, Mechanical, and Chemical Influences in
   Tissue Development	2
Inflammation in Mammalian Systems; Vascular Component,
   Cellular Component	3
Tissue Repair (scar) vs. Tissue Regeneration	3
Introduction to Extracellular Matrix: Components, Structure, 
   Function	3
Collagen as a Structural and Functional Protein	2
Synthetic and Naturally Ocurring Tissue Scaffolds	1
Co-cultures and Other In-vitro Systems for Promoting
   Differentiation and Tissue Remodeling	3
Response to Mammalian Synthetic Materials and Biomaterials	3
Scaffolds: CM Interactions	3
Role of Immune System in Tissue  Engineering - Autografts vs.
   Allografts vs.Xenografts	3
Cytokines, Growth Factors, Integrins, Signalling Peptides	3
Tissue Engineering and the Cardiovascular System	2
Tissue Engineering and the Musculoskeletal System	2
Tissue Engineering and the Urogenital System	2
Tissue Engineering and the Dermatologic and Central Nervous System 	3

For further information regarding the Biomedical Engineering Program at Purdue University contact the Biomedical Engineering Graduate Office at (317) 494-5730 bmeprogram@ecn.purdue.edu