ChE 697Z

Fundamentals of  Controlled Release and Pharmaceutical Engineering

3 credit hours
Spring semester, alternate years

instructor(s)
	N.A. Peppas

prerequisites
	None

description
	Description of controlled release devices and analysis of systems
 that release drugs, peptides or proteins.  Drug targeting and other
 pharmaceutical phenomena.

text
N.A. Peppas, Textbook of Controlled Release, in press.
R. Baker, Controlled Release of Biologically Active Agents, Wiley, New York, 1986.
E. Lightfoot, Transport Phenomena and Living Systems, Interscience, New York, 1974.

outline
		Topic	Number of Lectures
Introduction		1
Classification of Release Systems		1
Fundamentals of Diffusion		2
Fundamentals of Polymer Science		3
Stefan Maxell Equations		1
Nerst-Planck Equations		1
Irreversible Thermodynamics		2
Kedem Katchalsky Equations		1
Applications to Osmosis		1
Diffusion Controlled Devices		2
Oral Applications		1
Membrane Controlled Devices		2
Intrauterine Applications		1
Active and Passive Transport		1
Pinocytosis-Phagocytosis		1
Biodegradable Systems		3
Implants		1
Transdermal Devices		2
Osmotically Controlled Devices		1
Pumps and Minipumps		1
Swelling-Controlled Systems		3
Pulsatile Delivery		1
Regulated Systems		1
Microencapsulation		1
Microspheres		1
Targetting		2
Liposomes		1
Buccal Delivery		1
Ocular Delivery		1
Vaginal Delivery		1

For further information regarding the Biomedical Engineering Program at Purdue University contact the Biomedical Engineering Graduate Office at (317) 494-5730 bmeprogram@ecn.purdue.edu