ChE 658

Biomedical Phenomena


3 credit hours
Spring semester, alternate years

instructor(s)
	N. A. Peppas, F. Doyle III, E. M. Sevick-Muraca

prerequisites
	A graduate transport phenomena course (fluid mechanics and mass transfer)

description
Advanced treatment of physiological processes and design of extracorporeal
 devices using the fundamentals of fluid mechanics, heat and mass transfer,
 reaction engineering, thermodynamics, and heat and mass balances. 
 Navier-Strokes equations, viscoelastic physiological fluids, moving 
boundary value problems.  Multicomponent diffusion problems, Stefan-Maxwell
 equations, diffusion and reaction.  Applications to tissue engineering and
 cell behavior.

text
E. N. Lightfoot, Transport Phenomena and Living Systems, Interscience, N.Y., 1974.
A. C. Guyton, Textbook of Medical Physiology, Saunders, Philadelphia, 1989.

outline
	Topic		  Number of Lectures
Anatomy and composition of body	1
Introduction to physiological events	2
Rheological properties of blood	2
Rheology of synovial fluid	1
Rheology of cell membranes	1
Biomedical fluid mechanics	1
Flow of biological suspensions	2
Flow in elastic conduits	3
Microcirculations	2
Heat transfer in body	3
Mass transfer in biological systems; the Stefan-Maxwell equations	3
Passive and facilitated transport	1
Active transport and pinocytosis	2
Hemodialysis 	3
Gas transport in blood	1
Artificial lung	1
Artificial pancreas	1
Other Organs	1
Tissue engineering	2
Metabolic processes, pharmacokinetic models	1
Compartmental models	2
Biomedical optics	2
Biointerfacial phenomena	1
Protein adsorption	3
Cell receptors	1
Cell adhesion	2

For further information regarding the Biomedical Engineering Program at Purdue University contact the Biomedical Engineering Graduate Office at (317) 494-5730 bmeprogram@ecn.purdue.edu