CD57

NKCELLS

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
NC1	Purified	0.2 mg	Freeze-dried			IM0289
IgM (mouse)	Biotin	0.2 mg	Freeze-dried			IM0754
	Purified	100 tests	Liquid	IOTest		IM0465
	FITC	100 tests	Liquid	IOTest		IM0466

The CD57 antigen (HNK-1 antigen carbohydrate moiety) is an oligosaccharide with sulfated glucoronic acid residues that may be linked to a variety of polypeptides or lipids. In peripheral blood, it is found on a subset of cells with natural killer activity. It is confined to mononuclear cells, primarily large granular lymphocytes. Many of these CD57+ cells co-express the CD8 antigen and are a subset of suppressor / cytotoxic T cells. Cord blood T cells or Natural Killer (NK) cells lack the CD57 antigen. It is not expressed on red blood cells or on platelets but is present on some neuroectodermal tissues. NC1 antibody was evaluated during the Fifth International Workshop on Human Leukocyte Differentiation Antigens.

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