HLA-DR
Clone & Isotype | Conjugate | Size | Format | Line | | Part Number |
|
B8.12.2 | Purified | 0.2 mg | Freeze-dried | | | IM0108 |
IgG2b (mouse) | Biotin | 0.2 mg | Freeze-dried | | | IM0261 |
| Purified | 100 tests | Liquid | IOTest | | IM0462 |
| FITC | 100 tests | Liquid | IOTest | | IM0463 |
| PE | 100 tests | Liquid | IOTest | | IM0464 |
|
Immu-357 | FITC | 100 tests | Liquid | IOTest | | IM1638 |
IgG1 (mouse) | PE | 100 tests | Liquid | IOTest | | IM1639 |
| PE-Cy5 | 100 tests | Liquid | IOTest | | IM1849 |
|
H279 (I2) | Purified | 100 tests | Freeze-dried | COULTER CLONE | | 6602142 |
IgG2a (mouse) | FITC | 100 tests | Freeze-dried | COULTER CLONE | | 6602924 |
| RD1 | 100 tests | Liquid | COULTER CLONE | | 6602920 |
|
BL2 | Purified | 0.2 mg | Freeze-dried | | | IM0109 |
IgG2b (mouse) | | | | | | |
|
|
The recognized epitope is a monomorphic determinant of human HLA class II molecules with estimated molecular weights of 29-34 kDa. These molecules are found on Antigen-Presenting Cells (APC), i.e. B lymphocytes, monocytes, macrophages, and thymic epithelial cells. They are also expressed on activated T cells, but not on granulocytes, platelets, and red blood cells. The I2 antigen is absent from some homozygous typing cells which are DR7+ or DR11+. Resting T cells or endothelial cells that do not normally express these molecules can be induced to express them. These molecules are involved in cellular interactions among immuno-competent cells. I2 antibody was evaluated during the Fifth International Workshop on Human Leukocyte Differentiation Antigens.

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