CD25

IL-2 RECEPTOR

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
1HT44H3 (IL-2R1)	Purified	100 tests	Freeze-dried	COULTER CLONE		6603092
IgG2a (mouse)	FITC	100 tests	Freeze-dried	COULTER CLONE		6603200
B1.49.9	Purified	0.2 mg	Freeze-dried			IM0119
Ig2a (mouse)	Biotin	0.2 mg	Freeze-dried			IM0266
	Purified	100 tests	Liquid	IOTest		IM0477
	FITC	100 tests	Liquid	IOTest		IM0478
	PE	100 tests	Liquid	IOTest		IM0479
	PE-Cy5	100 tests	Liquid	IOTest		IM2044
33B3.1	Purified	0.2 mg	Freeze-dried			IM0317
IgG2a (rat)	FITC	100 tests	Liquid	IOTest		IM0481
CYTO-STATS

The CD25 (IL-2R1) antigen is a single-chain glycoprotein with a molecular weight of 55 kDa which is the low affinity receptor for IL-2 (IL-2Ra). In conjunction with p75 (CD122 antigen; IL-2Rb), CD25 antigen forms a high-affinity IL-2R complex. It is found on activated T and B cells, on activated macrophages and on T cell Clones. It is also expressed on Natural Killer (NK) cells enriched from peripheral blood lymphocytes by culturing in the presence of IL-2. It is absent from thymocytes and resting T and B cells. B1.49.9 antibody does not block the binding of IL-2 to its receptor. 33B3.1 antibody inhibits IL-2-driven cell proliferation. IL-2R1 and 33B3.1 antibodies were evaluated during the Second International Workshop on Human Leukocyte Differentiation Antigens. B1.49.9 antibody was evaluated during the Third Workshop.

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