CD15

GRANULOCYTES

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
CX7H12-4-7 (KC48)	FITC	0.5 mL	Liquid	COULTER		6607001
IgM (mouse)
* 0H5	Purified	0.2 mg	Freeze-dried			IM0165
IgM (mouse)	Purified	100 tests	Liquid	IOTest		IM0475
	FITC	100 tests	Liquid	IOTest		IM1423
	PE	100 tests	Liquid	IOTest		IM1954
	PE-Cy5	100 tests	Liquid	IOTest		IM2045

The CD15 antigen (Lewis x: Lex) is the lacto-N-fucopentaose III molecule. It is a branched pentasaccharide with a molecular weight of 185-200 kDa. This carbohydrate moiety can be found on glycolipids and on glycoproteins expressed on cell membrane.It is strongly expressed by neutrophils, eosinophils, monocytes and normal myeloid precursor cells. It is not expressed on normal erythrocytes, platelets or lymphocytes. 80H5 antibody recognizes an early myeloid differentiation epitope which is found on metamyelocytes, myelocytes and promyelocytes and activated macrophages. Both antibodies were evaluated during the Fifth International Workshop on Human Leukocyte Differentiation Antigens.

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