CD4

HELPER T CELLS

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
SFCI12T4D11 (T4)	Purified	100 tests	Freeze-dried	COULTER CLONE	IVD	6602138
IgG1 (mouse)	Biotin	100 tests	Freeze-dried	COULTER CLONE		6602416
	FITC	100 tests	Freeze-dried	COULTER CLONE	IVD	6602393
	RD1	100 tests	Liquid	COULTER CLONE	IVD	6602864
13B8.2	Purified	0.2 mg	Freeze-dried			IM0398
IgG1 (mouse)	Biotin	0.2 mg	Freeze-dried			IM0704
	Purified	100 tests	Liquid	IOTest		IM0447
	FITC	100 tests	Liquid	IOTest		IM0448
	PE	100 tests	Liquid	IOTest		IM0449
	PE-Cy5	100 tests	Liquid	IOTest		IM1574
BL4	Purified	0.2 mg	Freeze-dried			IM0115
IgG2a (mouse)	Biotin	0.2 mg	Freeze-dried			IM0263
CYTO-STATS

The CD4 antigen is a single-chain transmembrane glycoprotein with a 59 kDa molecular weight. It is found on a specific subset of peripheral blood lymphocytes, the so-called "helper" cells. It is present on most thymocytes where it is frequently co-expressed with CD8. CD4 is also expressed on all the monocytes, although with a lower density than on CD4+ T cells. CD4+ T cell subset is active in inducing and helping the synthesis of immunoglobulins by B cell. CD4 is an accessory molecule for MHC class II molecule recognition by helper T cells.CD4 is a receptor for the Human Immunodeficiency Virus (HIV). BL4 and 13B8.2 antibodies recognize different epitopes and are not cross-blocking. All three antibodies antagonize HIV effects in vitro. T4 antibody was evaluated during the First International Workshop on Human Leukocyte Differentiation Antigens. 13B8.2 and BL4 antibodies were evaluated during the Third Workshop.

---

---

© Coulter International Corporation, 1996. All rights reserved. Copyrights and Trademarks


Products are available FOR RESEARCH USE ONLY (RUO). Unless indicaed FOR IN VITRO DIAGNOSTIC USE (IVD)