CD14

MONOCYTES

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
116 (Mo2)	FITC	50 tests	Liquid	CYTO-STAT	IVD	6604114
IgM (mouse)	RD1	50 tests	Liquid	CYTO-STAT	IVD	6604500
322A-1 (MY4)	FITC	50 tests	Liquid	CYTO-STAT	IVD	6604110
IgG2b (mouse)				CYTO-STAT
Other mAbs

The CD14 antigen is a glycosyl-phosphatidylinositol-linked single-chain surface membrane glycoprotein with a molecular weight of 53-55 kDa. It functions as a high affinity receptor for the complex of lipopolysaccharide (LPS) and the LPS-binding protein (LBP). It is found on cells of myelomonocytic lineage. CD14 antigen is strongly expressed on monocytes, macrophages, and weakly on neutrophils. It is also weakly expressed on B cells; but is absent from T cells, null cells, red blood cells and platelets. It is found on Langerhans cells, follicular dendritic cells and histiocytes. The 116 (Mo2) and the 322A-1 (MY4) antibodies were characterized during the First International Workshop on Human Leukocyte Differentiation Antigens.

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