CD10

COMMON ACUTE LYMPHOCYTIC LEUKEMIA ANTIGEN (CALLA)

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
J5	FITC	50 tests	Liquid	CYTO-STAT		6604107
IgG2a (mouse)	RD1	50 tests	Liquid	CYTO-STAT		6604120
Other mAbs

The CD10 antigen is refered to as the Common Acute Lymphoblastic Leukemia Antigen (CALLA). It is a type II integral membrane protein, identified as the human membrane-associated neutral endopeptidase, with a molecular weight of 100 kDa. It is expressed on uncommitted lymphoid precursors. CD10 expression is lost as cells enter the T lineage. In the B lineage, CD10 expression is lost later, as cells acquire surface Ig expression. It is also expressed on activated and proliferating B cells in the germinal center and on neutrophils. J5 antibody was characterized during the First International Workshop on Human Leukocyte Differentiation Antigens.

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