CD8

SUPPRESSOR/CYTOTOXIC T CELLS

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
SFCI21Thy2D3 (T8)	FITC	50 tests	Liquid	CYTO-STAT	IVD	6603861
IgG1 (mouse)	RD1	50 tests	Liquid	CYTO-STAT	IVD	6603848
	ECD	50 tests	Liquid	CYTO-STAT		6604728
	PC5	50 tests	Liquid	CYTO-STAT		6607011
Other mAbs

The CD8 (T8) antigen is a disulfide-linked dimer.The molecular weight of each monomer is about 32-34 kDa. The CD8 molecule is found on a T cell subset of human peripheral blood lymphocytes called "cytotoxic / suppressor" cells. A subset of Natural Killer cells expresses the CD8 antigen but with low to medium density expression. It is also present on most thymocytes where it is frequently co-expressed with CD4 and on a subpopulation of bone marrow cells. The CD8 molecule acts with the T Cell Receptor as a co-receptor for MHC class I molecule in antigen recognition. This antibody recognizes the a chain of the CD8 molecule. T8 antibody was characterized during the First International Workshop on Human Leukocyte Differentiation Antigens.

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