Re: phosphatidylserine (PS) stain

c.reutelingsperger@bioch.rulimburg.nl
Wed, 14 Feb 1996 14:27:16 GMT

Annexin V is made available by BRAND Applications as a FITC conjugate
of 1:1 stoichiometry. This probe possesses full phospholipid binding
capacity and is highly sensitive for PS exposed by apoptotic cells.
It is a very bright probe, which distinguishes easily between
viable and early apoptotic cells. This is very nicely shown by
Seamus Martin et al. J.Exp.Med. 1995, 182; 1545-1556, who used
this probe to show that PS exposure is an early and general feature
of apoptosis regardless of the initiating trigger.

Since recently BRAND Applications changed its name to
NeXins Research BV.
This firm locates in the Netherlands and can be
contacted by:
phone: +31 165 503852
fax: + 31 165 502291
mail address: P.O.Box 16
4740 AA Hoeven.
the Netherlands.

Chris Reutelingsperger
Department of Biochemistry
University of Limburg
Maastricht, the Netherlands
E-mail. c.reutelingsperger@bioch.rulimburg.nl

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