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My problem is this: The Becton-Dickinson provides the D statistic and
the normalized D for use in hypothesis testing. The D lies between 0 and
1, always; the normalized D is a function of the sample sizes, and can
be any positive number. Dr. Kildare has been using the normalized D. I
explained that this was largely a measure of the number of B cells
entering the analysis, and not a measure of the difference between the
histograms. He should use the raw D, that lies between 0 and 1 (assuming
we are going to use this statistic at all.) Impossible, says Dr. Kildare:
the Mayo clinic uses the normalized D. "If they are, then they are mistake,"
I reply, "but I think they are using the raw D x 100. That is why their
"D" statistics are larger than 1." Dr. Kildare does not believe me; Mayo
clinic never mistaken, he claims; will not entertain possibility that they
are multiplying the D by hundred (which would be o.k.).
So can someone please tell me precisely what formula alleging to be that
of the Kolmogorov-Smirnov test statistic is being used by flow gurus at
the Mayo clinic, or a reference of Mayo provenance that I can show to
Dr. Kildare.
Thanks.
Catherine Dalzell,
beleagered statistician.
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CD-ROM Vol 3 was produced by Monica M. Shively and other staff at the
Purdue University Cytometry Laboratories and distributed free of charge
as an educational service to the cytometry community.
If you have any comments please direct them to
Dr. J. Paul Robinson, Professor & Director,
PUCL, Purdue University, West Lafayette, IN 47907.
Phone: (765)-494-0757;
FAX(765) 494-0517;
Web