Re: MHC-I antibodies

PAUL@flowcyt.cyto.purdue.edu
Thu, 13 Feb 1997 19:25:19

I have been asked to put this message out - please reply to the
address below not to me:
Thank you.
------- Forwarded Message Follows -------

>From Louise Furukawa
huge@itsa.ucsf.edu

> Greetings from San Francisco. My name is Louise Furukawa and I am
> post-doc at UCSF. I was referred to you by Enoc Hollemwegeuer at
> Pharmingen. One of my projects has revolved around down-regulating MHC-I
> on constituents on the vascular wall (endothelium, vascular smooth muscle
> cells, and fibroblasts). We are able to do this well, and can show
> decreased cytolysis of these so-modified endothelial cells by sensitized
> lymphocytes. I'd like to demonstrate that the killing is specific for
> MHC-I and am looking for an anti-MHC-I antibody that is directed to an
> epitope essential for the CTL TCR/MHC-I interaction. Do you know of any
> such antibody offhand or know of any article where they have done this?
> I'd appreciate any leads. Thanks a lot. Louise
--------------------------------------------------
J.Paul Robinson, Purdue University Cytometry Labs
Professor of Immunopharmacology
robinson@flowcyt.cyto.purdue.edu PH:317-494 6449 FAX:317-494 0517
web http://www.cyto.purdue.edu


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CD-ROM Vol 3 was produced by Monica M. Shively and other staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone: (765)-494-0757; FAX(765) 494-0517; Web http://www.cyto.purdue.edu , EMAIL cdrom3@flowcyt.cyto.purdue.edu