Chemotherapy

BMS 445, Spring 1996
G.L. Coppoc, DVM, PhD

Course Outline Menu

• Office Hours / Contact
• Use of Network
• References
• Format of Section
• Advice
• Issues Faced by Profession
• Drugs to Know
• Drug Groups

Office Hours / Contact
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• Lynn Hall G182
• Contact after class for questions or appointment
• Drop-in if door open
• Make appointment with secretary, G176
• Emergencies -- 49-48633 or home - 743-2719

References
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• TEXTBOOK
  Abbreviation: VPT7th96: Section 10: Chemotherapy of Microbial Diseases
  Section 11: Chemotherapy of Parasitic Diseases
  Section 12, Ch50: Chemotherapy of Neoplastic Diseases
  in Veterinary Pharmacology and Therapeutics
  7th edition, ed., H. Richard Adams, Iowa State University Press, Ames, 1996
  
• OTHER REFERENCES USED BY GLC
  • GG9th96: Godman & Gilman's The Pharmacological Basis of Therapeutics 9th edition, eds. J.G. Hardman, Lee E. Limbird, McGraw Hill, New York, 1996.
    
  • Brody2nd94: Human Pharmacology: Molecular to Clinical eds. T.M. Brody, J. Larner, K.P. Minneman, H.C. Neu, Mosby, St. Louis, 1994.
    
  • Armour, J., "Modern anthelmintics for farm animals", Chapter 10 in Pharmacological Basis of Large Animal Medicine, eds. J.A. Bogan, P. Lees, and A.T. Yoxall, Blackwell Scientific Publications, Boston, 1983. 565 pp.
    
  • Brander91: Brander, G.C., D.M. Pugh, R.J. Bywater, & W.L. Jenkins. 1991. Chapter 35, Antifungal and Antiviral agents. in Veterinary Applied Pharmacology & Therapeutics, 5th ed. . Bailliere Tindall, London.
    
  • USPDI94; USPDI95; USPDI96: United States Pharmacopeia Drug Information, USPC, 12601 Twinbrook Parkway, Rockville, MD 20852 (published annually with monthly updates).
    
  • VPB8th93: Veterinary Pharmaceuticals and Biologicals, 8th edition, 1993-1994. Veterinary Medicine Publishing Company, Lenexa Kansas. 1993.
    
  • Prescott&Baggot2nd93: Antimicrobial Therapy in Veterinary Medicine 2nd edition, eds. J.F. Prescott and J.D. Baggot, Iowa State University Press, Ames, 1993.
    
  • VDH2nd95: Veterinary Drug Handbook, 2nd edition, Donald C. Plumb, Iowa State University Press, Ames, 1995

Format of Section
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• Revamping notes extensively -- Copy of last year's in library on reserve
• New versions on Web
• Lecture
• Study Questions
• Discussion
• Cases
• Independent Study
• MEDIC

Issues Being Faced by Profession
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• Food safety
• Antibiotic resistance
• Responsibility to animals
• Responsibility to clients
• Responsibility to profession

Advice
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This section on chemotherapy includes a massive load of drug categories, names, mechanisms of action, pharmacokinetic properties, adverse effects, and major indications. It can be overwhelming if one does not keep up! It is guaranteed that you will not be able to master the material in the week before the exam.

An excellent approach to this material is to first be sure you know the various categories of drugs that will be presented and the drugs that belong to those categories. Except for very commonly used drugs and drugs that constitute important prototypes, for this course we will assume that members of the group inherit group characteristics. Therefore, a reasonable approach is as follows:

• Understand and be able to describe mechanisms of action of the drug groups
• Understand and be able to describe the basis of selectivity of each drug group
• Know the various schemes by which the drugs are categorized
• Know and be able to write the names of major members of each drug group / category
• Be able to assign all drugs discussed to a category on a "recognition" basis. to learn the groups, members of the groups, and major group characteristics
  
  
  

Gordon L. Coppoc, DVM, PhD
Professor and Head
Department of Basic Medical Sciences
School of Veterinary Medicine
Purdue University
West Lafayette, IN 47907-1246
Tel: 317-494-8633
Fax: 317-494-0781

Last modified by GLC 9:33 AM on 3/15/96