Specialty Training & Education Program

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Ligand - Receptor Interaction, Cell Adhesion and Whole Blood Cytometry

University of New Mexico
Cytometry Laboratory
University of New Mexico School of Medicine
900 Camino de Salud, NE
Albuquerque, New Mexico 87131-5636 
Laboratory Profile

Head: Larry A. Sklar, Ph.D.; Technical Director: Larry Seamer, BS, MT (ASCP)

1. Facilities: 3000 square foot facility containing instrumentation lab, general biology lab, computer facilities, tissue culture facility, molecular biology facility for preparation of vectors, transfection, and expression.

2. Instrumentation:
Flow cytometry: FACScan (2), Epics Elite, Epics 753.
Other major items: Hitachi spectrophotometer; SLM 8000 spectrofluorometer; SLM 4850 MHF spectrofluorometer; Applied Photophysics DX. 18 double mix spectrophotometer; Zeiss phase-contrast microscope; Meridian InSIGHT plus laser scanning, confocal microscope; Beckman elutriator centrifuge.

3. Specialization Areas:
Ligand-receptor analysis: Receptor site number; binding constants and rates; receptor internalization; computational modeling.
Whole blood cytometry: Physiology of cells in blood; adhesive interactions; receptor expression; leukocyte-platelet interactions.
Cell-cell interactions: Heterotypic and homotypic adhesion analysis; receptor expression.

4. Special Opportunities: Ligand-receptor interactions: Ligand-receptor analysis and modeling. Isolation, preparation, handling of human neutrophils. Handling of blood; assay of priming and receptor expression in patient samples.

5. Special Courses Offered: None at this time.

6. Graduate Program: Mentors associated with UNM Structural Biology Center and Cytometry Laboratory.

7. Local Accommodations: Nearby hotels and motels ranging from $25 - $75 per day. Closest is one mile. Some provide van transportation to UNM.

8. Transportation: Local airport is Albuquerque International, 4 miles from UNM; cab is approximately $6.00

9. Cost of Internship: Negotiable.

10. Communication:

Larry A Sklar, Ph.D.
Professor of Pathology
University of New Mexico School of Medicine
Cytometry/UNM Cancer Center, Room 325
900 Camino de Salud, NE
Albuquerque, New Mexico 87131-5636

Phone: (505) 277-7249
FAX: (505) 277-6677

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If you have suggestions or comments related to the STEP Program in general, problems with this particular page, or you want to know how to be a STEP program lab, send me an email message now jpr@flowcyt.cyto.purdue.edu or contact me at the address below.