SPIE Call for Papers and Announcement

Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VI (Conference BO124)

Part of SPIE's International Symposium on Biomedical Optics (BiOS) 2008, Program Track on Biomedical Spectroscopy, Microscopy, and Imaging, 19–24 January 2008
 San Jose Convention Center San Jose, CA USA

Conference Chairs:

Daniel L. Farkas, Cedars-Sinai Medical Ctr.; Dan V. Nicolau, The Univ. of Liverpool (United Kingdom); Robert C. Leif, Newport Instruments

Conference Co-Chairs:

J. Paul Robinson, Purdue Univ.; Attila Tarnok, Univ. Leipzig (Germany); Ramesh Raghavachari, U.S. Food and Drug Administration

Program Committee:

Christopher H. Contag, Stanford Univ.; Paul Dan A. Cristea, Univ. Politehnica Bucharest (Romania); Alberto Diaspro, Univ. degli Studi di Genova (Italy); Erik G. Fällman, Umeå Univ. (Sweden); Jesper Glückstad, Danmarks Tekniske Univ. (Denmark); Ewa M. Goldys, Macquarie Univ. (Australia); James F. Leary, Purdue Univ.; Charles P. Lin, Massachusetts General Hospital; Andreas Nowatzyk, Cedars-Sinai Medical Center; Markus Sauer, Univ. Bielefeld (Germany)

This interdisciplinary conference addresses the knowledge continuum from molecular structure and fundamental mechanisms to biological and medical applications, focusing on new approaches to imaging, manipulation, and analysis of biomolecules, cells and tissues, both in vitro and in vivo. The conference will report on the latest developments in functional and multispectral imaging, optical manipulation, analytical cytology (cytomics), cellular imaging algorithms and quantification. The principal aim is to further improve the interdisciplinary dialog between those who design and implement critical technologies and the primary users who study important problems that drive developments, in order to advance translational research.

Reports of original research contributions are solicited on the following topics:

Functional imaging of biomolecules, live cells and tissues:

• light microscopy of living cells and tissues (2D, 3D, 4D)
• spectral imaging of multiple cellular and tissue components
• new and automated methods for monitoring biological structure and physiology
• microscopic imaging of electric potentials and events
• mesoscopic (microscopic resolution in vivo) tissue imaging
• multimodality tissue imaging in vivo.

Biophotonic techniques for regenerative medicine:

• stem cell characterization in vitro
• stem cell imaging and tracking in vivo
• in vivo studies of immunologic events
• imaging methods in organ transplantation
• functional monitoring of tissue engineering constructs
• imaging of tissue oxygenation and vascularization.
• Optical manipulation of cells and tissues:
• cell micromanipulation using optical trapping
• cellular effects of localized energy deposition into micro- and nano-absorbers
• cells and biomolecules in micro- and nanoconfined spaces
• scanning probe microscopy of cells and surface-immobilized biomolecules.

Spectral imaging (microscopic and macroscopic)

• spectral pathology
• small animal imaging
• clinical applications.

Fluorescence and phosphorescence lifetime imaging

• probes, including new dyes
• high throughput cytometry
• in situ diagnostic applications.

Multimode optical imaging

• tools and approaches for combining several optical imaging methods
• advanced registration and visualization.

Microarrays for biomolecules, cells and tissues

• printing technologies
• readout methods, including image analysis and quantification
• applications of microarrays in diagnostics and drug discovery.

Advanced analytical cytology of cells (cytomics):

• new technologies for multispectral and multiparameter imaging, including acquisition, segmentation and analysis methods
• new components for analytical cytology instru-mentation, including ultraminiature and nano- systems.

Rare event detection

• new methods for cell separation including high-speed, optical and magnetic-paramagnetic sorting
• circulating stem, fetal, cancer, and other rare cells
• digital imaging for quantitative pathology.

Clinical & research applications of analytical cytology

• new and unusual applications of analytical cytology.

Image and data processing, quantification, standards, and display methods:

• cell-based high throughput and high content screening
• clustering algorithms
• analytical quantification, including new methods for multiparameter cell analysis and data manipulation
• automated 3D image processing, including tracking of tissue section surfaces, image segmentation, and fluorometry/densitometry
• software standards and regulatory requirements for spectroscopy, flow cytometry, and imaging
• image formats, databasing and retrieval
• advanced image registration and display methods, including co-display of image sets.

The call for papers is located at http://spie.org/x7777.xml

Please send technical questions to Robert C. Leif