Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues III (BO121)

Part of SPIE’s International Symposium on Biomedical Optics 2006

21-26 January 2006 • San Jose Convention Center • San Jose, CA, USA


Conference Chairs: Daniel L. Farkas, Cedars-Sinai Medical Ctr.; Robert C. Leif, Newport Instruments; Dan V. Nicolau, Swinburne Univ. of Technology (Australia)

Co-Chairs: Paul Robinson, Purdue Univ.; James Leary, University of Texas, Galvertson?


Program Committee: Paul Dan A. Cristea, Univ. Politehnica Bucuresti (Romania); Alberto Diaspro, Univ. degli Studi di Genova (Italy); Erik G. Fällman, Umeä Univ. (Sweden); Ewa Goldys, Macquarie Uni. (Australia); Jesper Glückstad, Risø National Lab. (Denmark); Andreas Nowatzyk, Carnegie Mellon Univ.; Marcus Sauer, Univ. Bielefeld (Germany); Attila Tarnok, Univ. Leipzig (Germany)


This interdisciplinary conference focuses on the knowledge continuum starting from fundamental aspects down to the applications of imaging, manipulation, analysis and quantification of biomolecules, cells and tissues, both in vivo and in vitro. The conference will report on the latest developments in functional imaging, multispectral imaging, optical manipulation, analytical cytology (cytomics), imaging algorithms and quantification. The principal aim of this conference is to further improve on the interdisciplinary dialog between those who define and implement critical technologies and the primary users who study important problems that drive developments.


    Reports of original research contributions are solicited on the following topics:


    Functional imaging and optical manipulation of biomolecules, live cells and tissues:

•   light microscopy of living cells and tissues (2D, 3D, 4D)

•   new and automated methods for monitoring biological structure and physiology

•   high spatial resolution microscopy methods for cell imaging (atomic force, near-field, etc.)

•   multicolor and spectral imaging of multiple cellular and tissue components

•   fluorescence and phosphorescence lifetime imaging

•   cell micromanipulation using laser tweezers and laser scissors

•   microscopic imaging of electric potentials and events

•   microscopic resolution optical and multimodality tissue imaging in vivo.


    Advanced techniques in analytical cytology (cytomics) of fixed cells:

•   multispectral and multiparameter imaging and measurements, including acquisition and analysis methods

•   fluorescence and luminescence lifetime imaging in cells and tissues

•   probes, including new dyes

•   high throughput cytometry

•   new methods and technology for cell separation including high-speed sorting and analysis of cells and other biological objects and magnetic-paramagnetic particles

•   new components for analytical cytology instrumentation, including ultraminiature and nano systems

•   new and unusual applications of analytical cytology.


    Image data processing and quantification methods:

•   cell-based high throughput/high content screening

•   clustering algorithms

•   analytical quantification including: new algorithms and methods for multiparameter cell analysis and data manipulation, as well as software standards

•   automated 3D image processing including tracking tissue section surfaces, 3D image segmentation, and 3D image fluorometry/densitometry

•   microarray methods for cells and tissues




Abstract Due Date: 11 July 2005

Manuscripts Due Week of: 2 January 2006


Please send technical questions to Robert C. Leif, email

The call for papers is located at