Known or Potential Interferents

• Cellular Elements
  • Platelet clumps or giant platelets
  • nucleated cells or fragments

• RBC Inclusions
  • Howell-Jolly bodies
  • Heinz or Pappenheimer bodies
  • parasites (malaris, babesia)

• Miscellaneous causes
  • Autofluorescence (drugs, porphyria)
  • RBC aggregation (paraproteins, cold agglutinins)
  • coincidence (eg. platelet and RBC)
  • abnormal RBCs, hemolysis

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